Assessing risk factors for complications in computer tomography-guided lung biopsy: quantitative analysis for predicting pneumothorax
Assessing risk factors for complications in computer tomography-guided lung biopsy: quantitative analysis for predicting pneumothorax
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BACKGROUND: Computer tomography (CT)-guided lung biopsy carries the risk of pneumothorax.A variety of other risk factors affect the occurrence of pneumothorax.OBJECTIVE: Assess the incidence and risk factors associated with pneumothorax complications in CT-guided lung biopsy, and to conduct a quantitative analysis of the variables among the significant risk factors to identify more effective indicators for predicting pneumothorax complications.DESIGN: Retrospective logistic SETTING: Single center in China PATIENTS AND METHODS: From June 2017 to May 2021, consecutive patients who underwent CT-guided lung biopsy were identified from the medical record system.Binary logistic regression analysis was used to identify potential risk factors for pneumothorax.
Receiver operating characteristic (ROC) curves hp pavilion 15-eg1053cl were constructed for continuous variables to determine cutoff values that optimized sensitivity and specificity.MAIN OUTCOME MEASURES: The incidence and risk factors of pneumothorax in CT-guided lung biopsy.SAMPLE SIZE: 132 patients RESULTS: The incidence of pneumothorax was 28.9% (38/132), with 6.8% (9/132) of patients requiring chest tube insertion.
Results indicated that smaller lesion size (OR 0.724; 95% CI 0.619-0.848; P=.0001), longer needle tract length (OR 1.
320; 95% CI 1.145-1.521; P=.001), multiple passes through the pleura (OR 4.618; 95% CI 1.
378-15.467; P=.013), and needle tract length/lesion diameter (L/D) ratio (OR 0.028; 95% CI 0.002-0.
732; P=.007) were independent risk click here factors for pneumothorax.ROC curve analysis determined a cut-off value of 0.81 for the L/D ratio (sensitivity=89.5%, specificity=71.
3%).The area under the ROC curve (AUC) values of maximum diameter, needle tract length, and L/D ratio for pneumothorax were 0.749, 0.812, and 0.850, respectively.
CONCLUSIONS: The L/D ratio, multiple passes through the pleura, longer needle tract length, and smaller lesions were independent risk factors for pneumothorax.A L/D ratio of less than 0.81 may indicate a pneumothorax.It may be necessary to use the proper sealing procedure for this patient group.LIMITATIONS: Due to its retrospective nature, there may be inherent selection bias.